GLYCINE BIOULTRA FOR MOLECULAR BIOLOGY >= 99.0 % NT (C005B-049042)

Application

Glycine has been used as a component of the viral extraction mixture for adenovirus viral extraction.

Biochem/physiol Actions

Glycine is a non-essential amino acid. It is involved in the synthesis of purines, serine and porphyrins. Glycine-gated channels mediate the influx of calcium through cell membranes. It also acts as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors. In cancer cells, the synthesis of glycine might be increased due to increased demand for the amino acid.

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Molecular Weight: 75.07. Empirical Formula: C₂H₅NO₂. linearFormula: NH₂CH₂COOH. grade: for molecular biology. Quality Level: 200. product line: BioUltra. Assay: ≥. 99.0% (NT). form: crystalline. impurities: DNases, none detected, RNases, none detected, insoluble matter, passes filter test, phosphatases, none detected, proteases, none detected. ign. residue: ≤. 0.05% (as SO₄). loss: ≤. 0.05% loss on drying, HV, 20-26 °C. color: white. pKa (25 °C): (1) 2.35, (2) 9.60, 2.35. mp: 240 . °C (dec.) (lit.). solubility: 1 M HCl: 1 . M at . 20 . °C, clear, colorless. anion traces: chloride (Cl^-): ≤. 50 . mg/kg, sulfate (SO₄^2-): ≤. 100 . mg/kg. cation traces: Al: ≤. 5 . mg/kg, As: ≤. 0.1 . mg/kg, Ba: ≤. 5 . mg/kg, Bi: ≤. 5 . mg/kg, Ca: ≤. 10 . mg/kg, Cd: ≤. 5 . mg/kg, Co: ≤. 5 . mg/kg, Cr: ≤. 5 . mg/kg, Cu: ≤. 5 . mg/kg, Fe: ≤. 5 . mg/kg, K: ≤. 50 . mg/kg, Li: ≤. 5 . mg/kg, Mg: ≤. 5 . mg/kg, Mn: ≤. 5 . mg/kg, Mo: ≤. 5 . mg/kg, NH₄⁺: ≤. 200 . mg/kg, Na: ≤. 100 . mg/kg, Ni: ≤. 5 . mg/kg, Pb: ≤. 5 . mg/kg, Sr: ≤. 5 . mg/kg, Zn: ≤. 5 . mg/kg. SMILES string: NCC(O): O. λ: 1 . M in 1 M HCl. UV absorption: λ. : 260 . nm A_max: 0.05, λ. : 280 . nm A_max: 0.05. InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5). InChI key: DHMQDGOQFOQNFH-UHFFFAOYSA-N. Gene Information: rat ... Grin2a(24409). Storage Class Code: 13 - Non Combustible Solids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).