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glp-26 (c09-1135-820)

GLP-26 (C007B-358048)

Catalog No.
C007B-358048
Manufacturer No.
G651961-5mg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA

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GLP-26 is a HBV capsid assembly modulators (CAM), inhibits HBV DNA replication in Hep AD38 system ( IC 50 =3 nM), and reduces cccDNA by >:90% at 1 μM.GLP-26 disrupts the encapsidation of pre-genomic RNA, causes nucleocapsid disassembly and reduces

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GLP-26 is a HBV capsid assembly modulators (CAM), inhibits HBV DNA replication in Hep AD38 system ( IC 50 =3 nM), and reduces cccDNA by >90% at 1 μM.GLP-26 disrupts the encapsidation of pre-genomic RNA, causes nucleocapsid disassembly and reduces cccDNA pools.In VitroGLP-26 (0.7-1.7 μM; 3 days) reduces secreted HBeAg in HepNTCP-DL cells transfected with HBV/nwild type, with EC 50 values of 0.7 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability AssayCell Line: HepNTCP-DL cells Concentration: 0.7-1.7 μM Incubation Time: 3 days Result: Reduced secreted HBeAg in HepNTCP-DL cells.Form:Solid.

Specifications and Purity: ≥98%

Molecular Formula: C19H17F2N3O3

Molecular Weight: 373.35

PubChem CID: 130408536

Isomeric SMILES: CC1=C(N(C(=C1C(=O)C(=O)NCC#C)C)C)C(=O)NC2=CC(=C(C=C2)F)F

UPC:
41115710
Condition:
New
HazmatClass:
No
WeightUOM:
LB
MPN:
G651961-5mg
CAS:
2133017-36-2
Product Size:
5mg

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