A cell-permeable non-steroidal antagonist of GPER, inhibiting activation by either 17&beta-estradiol or the GPER-selective agonist G-1 (IC50 = 112 and 165 nM, respectively) has no detectable binding activity to either ER&alpha or
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A cell-permeable non-steroidal antagonist of GPER, inhibiting activation by either 17β-estradiol or the GPER-selective agonist G-1 (IC50 = 112 and 165 nM, respectively); has no detectable binding activity to either ERα or ERβ.
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