G-1-10 mg

Catalog No.: C003B-381466
Manufacturer No.: 10008933-10
Manufacturer Name: CAYMAN CHEMICAL
Quantity: 1
Unit of Measure: EA

G-1 is a nonsteroidal, high-affinity, selective agonist of GPR30 that binds with a Ki value of 11 nM. Competitive binding studies in endoplasmic reticulum &alpha- (ER&alpha-) and ER&beta-expressing cells yielded Ki values for estradiol of 0.

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Description
Specifications

G-1 is a nonsteroidal, high-affinity, selective agonist of GPR30 that binds with a Ki value of 11 nM. Competitive binding studies in endoplasmic reticulum α- (ERα-) and ERβ-expressing cells yielded Ki values for estradiol of 0.30 and 0.38 nM, respectively, with no substantial binding of G-1 at 1 µM. The discovery of G-1, a compound that does not bind classical ERs, should facilitate further physiological experiments to define the role of GPR30 in vivo.

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UPC:: 41105318
HazmatClass:: Yes
WeightUOM:: LB
MPN:: 10008933-10
CAS:: 881639-98-1

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