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fmoc-ser(tbu)-oh (c15-1259-613)

FMOC-SER(TBU)-OH >=98.0% (C005B-058749)

Catalog No.
C005B-058749
Manufacturer No.
47619-25G-F
Manufacturer Name
Sigma-Aldrich
Quantity
25
Unit of Measure
GR

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Application Fmoc-Ser(tBu)-OH is an N -terminal protected reagent used in the peptide synthesis. Some of the reported examples are: Total synthesis of an antibiotic, daptomycin, by cyclization via a chemoselective serine ligation.

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Application

Fmoc-Ser(tBu)-OH is an N-terminal protected reagent used in the peptide synthesis. Some of the reported examples are:

  • Total synthesis of an antibiotic, daptomycin, by cyclization via a chemoselective serine ligation.
  • Preparation of MUC1, a T-cell helper peptide, using iterative pentafluorophenyl ester-mediated fragment condensations.
  • Linear solid-phase peptide synthesis of ubiquitin and diubiquitin.

Molecular Weight: 383.44. Empirical Formula: C22H25NO5. Quality Level: 100. Assay: ≥. 98.0% (HPLC). form: powder. optical activity: [α. ]20/D +25.5±1°, c :  . 1% in ethyl acetate. reaction suitability: reaction type: Fmoc solid-phase peptide synthesis. application(s): peptide synthesis. functional group: Fmoc. storage temp.: 2-8°C. SMILES string: CC(C)(C)OC[C@H](NC(: O)OCC1c2ccccc2-c3ccccc13)C(O): O. InChI: 1S/C22H25NO5/c1-22(2,3)28-13-19(20(24)25)23-21(26)27-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,23,26)(H,24,25)/t19-/m0/s1. InChI key: REITVGIIZHFVGU-IBGZPJMESA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).
UPC:
12141802
Condition:
New
HazmatClass:
No
MPN:
47619-25G-F
CAS:
71989-33-8

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