FLUNIXIN MEGLUMINE (C005B-039602)

Application

Flunixin meglumine has been used as a nonsteroidal anti-inflammatory drug standard in electrospray ionization mass spectrometry (LC-ESI/MS).

Flunixin meglumine (IC₅₀ = 1 nM) can be used as a drug for animals for the management of intestinal ischaemia, colic, and endotoxemia in horses.

Biochem/physiol Actions

Flunixin meglumine is a nonsteroidal anti-inflammatory drug, which blocks prostaglandin synthesis.

COX1, COX2 and PLA2 inhibitor non-narcotic analgesic, anti-pyretic, anti-inflammatory.

Molecular Weight: 491.46. Empirical Formula: C₁₄H₁₁F₃N₂O₂·C₇H₁₇NO₅. Quality Level: 100. Assay: ≥. 98% (HPLC). form: powder. color: white to beige. mp: 136.6-137.4 . °C. solubility: H₂O: freely soluble. storage temp.: room temp. SMILES string: CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.Cc1c(Nc2ncccc2C(O): O)cccc1C(F)(F)F. InChI: 1S/C14H11F3N2O2.C7H17NO5/c1-8-10(14(15,16)17)5-2-6-11(8)19-12-9(13(20)21)4-3-7-18-12. 1-8-2-4(10)6(12)7(13)5(11)3-9/h2-7H,1H3,(H,18,19)(H,20,21). 4-13H,2-3H2,1H3/t. 4-,5+,6+,7+/m.0/s1. InChI key: MGCCHNLNRBULBU-WZTVWXICSA-N. Pictograms: GHS07. Signal Word: Warning. Hazard Statements: H315 - H319 - H335. Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338. Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3. Target Organs: Respiratory system. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves.