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flt-3/flk-2 ligand human

FLT-3/FLK-2 LIGAND HUMAN RECOMBINANT

Catalog No.
C005B-181794
Manufacturer No.
F3422-5UG
Manufacturer Name
Sigma-Aldrich
Quantity
5
Unit of Measure
UG

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Mouse and human Flt-3 ligand share ~72% homology and both demonstrate cross-species activity. Biochem/physiol Actions Flt-3/Flk-2 Ligand (FL, or Flt-3L) is a transmembrane glycoprotein that binds and activates the Flt-3 receptor.

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General description

Mouse and human Flt-3 ligand share ~72% homology and both demonstrate cross-species activity.

Biochem/physiol Actions

Flt-3/Flk-2 Ligand (FL, or Flt-3L) is a transmembrane glycoprotein that binds and activates the Flt-3 receptor. Expression of Flt-3 is primarily restricted among hematopoietic cells to the most primitive progenitor cells.

Physical form

Lyophilized, 0.2 μm sterile filtered, with with 0.5x PBS.

Analysis Note

The biological activity is measured by its ability to stimulate the proliferation of human AML5 cells.

biological source: human. Quality Level: 100. recombinant: expressed in E. coli. Assay: ≥. 98% (SDS-PAGE and HPLC). form: lyophilized powder. potency: ≤. 1.0 . ng/mL. mol wt: 17.6 . kDa. packaging: pkg of 5 . μ. g. storage condition: avoid repeated freeze/thaw cycles. technique(s): cell culture | mammalian: suitable. impurities: endotoxin, tested. web metadata keyword.default: primative hematopoietic cells, progenitor cells. UniProt accession no.: P36888. storage temp.: −. 20°C. Gene Information: human ... FLT3(2322). Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).
UPC:
51111603
Condition:
New
HazmatClass:
No
MPN:
F3422-5UG

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