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flagellin from salmonella typhimurium

FLAGELLIN FROM SALMONELLA TYPHIMURIUM

Catalog No.
C005B-305784
Manufacturer No.
SRP8029-10UG
Manufacturer Name
Sigma-Aldrich
Quantity
1
Unit of Measure
EA

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General description FliC (flagellin) is the subunit protein which polymerizes to form the filaments of bacterial flagella. The protein has four-domains (D0, D1, D2, D3).

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General description

FliC (flagellin) is the subunit protein which polymerizes to form the filaments of bacterial flagella. The protein has four-domains (D0, D1, D2, D3).

The encoded flagellin filament contains 55 kDa monomers.

Biochem/physiol Actions

FliC (flagellin) can activate the innate immune system by TLR5 (toll like receptor 5) and is an important proinflammatory molecule. FliC also induces the production of antibodies and is identified as an antigen by CD4+ T cells.

It also stimulates the production of proinflammatory mediators : nitric oxide, interleukin 1 (IL-1), IL-6, IL-8, and tumor necrosis factor α.

Physical form

Lyophilized from PBS.

Reconstitution

Reconstitute with 100 μL deionized water.

UPC:
51201619
Condition:
New
HazmatClass:
No
MPN:
SRP8029-10UG
CAS:
12777-81-0
Temperature Control Device:
Yes

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