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FIBROBLAST GROWTH FACTOR-BASIC FGF-BASIC FROM HUMAN RECOMBINANT EXPRESSED IN E. COLI CARRIER FREE (C005B-181809)

Catalog No.
C005B-181809
Manufacturer No.
F3685-4X25UG
Manufacturer Name
Sigma-Aldrich
Quantity
4
Unit of Measure
UG

Since FGF-Basic is found in a variety of organs, acts on a wide range of cell types, and has multifunctional actions, it has acquired numerous synonyms, including heparin-binding growth factor (class II or beta), eye-derived growth factor I,

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General description

Since FGF-Basic is found in a variety of organs, acts on a wide range of cell types, and has multifunctional actions, it has acquired numerous synonyms, including heparin-binding growth factor (class II or beta), eye-derived growth factor I, cartilage-derived growth factor, and astroglial growth factor II5. Purified bovine and human FGF-basic differ by 3 amino acids in sequence3, and are biologically and immunologically cross-reactive.

Citation

1. Gospodarowicz, D., Localization of a fibroblast growth factor and its effect alone and with hydrocortisone on 3T3 cell growth. Nature, 249, 123-127 (1974).
2. Gospodarowicz, D. et al., Structural characterization and biological functions of fibroblast growth factor. Endo. Rev., 8, 95-114 (1987).
3. Esch, F. et al., Primary structure of bovine pituitary basic fibroblast growth factor (FGF) and comparison with the amino-terminal sequence of bovine brain acidic FGF. Proc. Natl. Acad. Sci. USA, 82, 6507-6511 (1985).
4. Neufeld, G., and Gospodarowicz, D., Basic and acidic fibroblast growth factors interact with the same cell surface receptors. J. Biol. Chem., 261, 5631-5637 (1986).
5. Lobb, R.R. et al., Purification of heparin-binding growth factors. Anal. Biochem., 154, 1-14 (1986).
6. Abraham, J.A., Human basic fibroblast growth factor: nucleotide sequence and genomic organization. EMBO J., 5, 2523- 2528 (1986).

biological source: human. Quality Level: 200. recombinant: expressed in E. coli. Assay: ≥. 97% (SDS-PAGE). form: lyophilized powder. potency: <. 1 . ng/mL Biological Activity EC50. mol wt: 16.0 . kDa. packaging: pkg of 4X25 . μ. g, pkg of 25 . μ. g. storage condition: avoid repeated freeze/thaw cycles. color: white to faint yellow cast. solubility: water: soluble 0.025 . mg, clear, colorless to faintly yellow. UniProt accession no.: P09038. storage temp.: −. 20°C. Gene Information: human ... FGF2(2247). Storage Class Code: 10 - Combustible liquids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.
UPC:
51131801
Condition:
New
HazmatClass:
No
MPN:
F3685-4X25UG
Temperature Control Device:
Yes

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