Evodiamine is a quinozole alkaloid isolated from Evodia rutaecarpa, described as an agonist of the VR1 (vanilloid receptor subtype 1, TRPV1) with affinity (Ki = 5.95 microM) comparable to that of the prototypical VR1 chemical activator Capsaicin .Evodiamine induction of 45Ca2+ uptake was competitively antagonized by the Capsaicin antagonist Capsazepine .Evodiamine is described to inhibit prostaglandin E2 synthesis, cyclooxygenase-2 induction and NF-κB activation, producing antiinflammatory effects.An antiangiogenic and antiinflammatory agonist of TRPV1.
Specifications and Purity: ≥98%
Molecular Formula: C19H17N3O
Molecular Weight: 303.37
PubChem CID: 151289
Isomeric SMILES: CN1C2C3=C(CCN2C(=O)C4=CC=CC=C41)C5=CC=CC=C5N3
Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/E140884-SCI_ea0580dd6d5af823a718657b1ef34681.pdf
- UPC:
- 12142006
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- E140884-5g
- CAS:
- 518-18-3
- Product Size:
- 5g
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