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etravirine (tmc125)

Etravirine (TMC125) (C007B-154451)

Catalog No.
C007B-154451
Manufacturer No.
E408338-1ml
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA

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InformationEtravirine (TMC125) Etravirine (TMC125, R-165335) is a non-nucleoside reverse transcriptase inhibitor ( NNRTI ) used for the treatment of HIV.In vitroEtravirine (TMC125), is highly active against wild-type HIV-1 with EC50 of 1.4 nM to 4.8

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InformationEtravirine (TMC125) Etravirine (TMC125, R-165335) is a non-nucleoside reverse transcriptase inhibitor ( NNRTI ) used for the treatment of HIV.In vitroEtravirine (TMC125), is highly active against wild-type HIV-1 with EC50 of 1.4 nM to 4.8 nM and shows some activity against HIV-2 with EC50 of 3.5 μM. TMC125 also inhibits a series of HIV-1 group M subtypes and circulating recombinant forms and a group O virus.In vivoEtravirine has a high genetic barrier to the development of resistance. In phase IIb trials in treatment-experienced patients, including those infected with virus resistant to NNRTIs and protease inhibitors (PIs), TMC125 is active against HIV resistant to currently available NNRTIs, with a similar tolerability profile to that of the control group.Cell Datacell lines：Concentrations：Incubation Time：Powder Purity:≥95%.

Specifications and Purity: 10mM in DMSO

Molecular Formula: C20H15BrN6O

Molecular Weight: 435.28

UPC:
51111707
Condition:
New
HazmatClass:
No
WeightUOM:
LB
MPN:
E408338-1ml
CAS:
269055-15-4
Product Size:
1ml

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