ERK Inhibitor is a cell-permeable thiazolidinedione compound that shows anti-proliferative properties. Binds preferentially to ERK2 with a KD of ~5 μM and prevents its interaction with protein substrates. The compound has been shown to block ERK-mediated phosphorylation of ribosomal S6 kinase-1 (RSK-1) and ternary complex factor Elk-1 in HeLa cells, while exhibiting minimal effect on ERK1/2 phosphorylation by MEK1/2.
Specifications and Purity: ≥95%
Molecular Formula: C14H16N2O3S•HCl
Molecular Weight: 328.81
PubChem CID: 16218944
Isomeric SMILES: CCOC1=CC=C(C=C1)C=C2C(=O)N(C(=O)S2)CCN.Cl
Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/E335372-SCI_ac34a2499781232b61d5aee18ee6cbcc.pdf
- UPC:
- 51131506
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- E335372-100mg
- CAS:
- 1049738-54-6
- Product Size:
- 100mg
- Precautionary Statement Codes:
- P264
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