ENDOTOXIN REMOVAL RESIN, 1L

EndotoxinOUTTM was designed for the rapid removal of endotoxins and pyrogens (LPS, lipopolysaccharides) from nucleic acid (DNA) samples. EndotoxinOUTTM is an ideal product for the cleanup of buffers, cell culture media, protein solutions, nucleic acid (DNA) samples and pharmacological components. EndotoxinOUTTM consists of 6% cross-linked agarose covalently linked to polymyxin B to bind and remove harmful pyrogens from a solution. Polymyxin B is a family, polymyxin B1 and B2, of antibiotics that bind to the negatively charged site of the lipid A portion of the bacterial lipopolysaccharide layer, neutralizing the endotoxic activity. The covalently coupled agarose and polymyxin B is a stable matrix that resists leaching. EndotoxinOUTTM kit is supplied with a regneration buffer, endotoxin free water and 5 x 1ml columns. Click here to request bulk or custom sizes . Features Polymyxin B Sulfate immobilized on 6% cross-linked agarose Capacity: =9995 endotoxin units (EU) removed by 1ml resin from 5ml test containing 10,000EU Minimal leaching Reusable at least 10 times Applications Cleanup of buffers, cell culture media, protein solutions, DNA samples & pharmacological components Rapid 99.95% removal of endotoxins & pyrogens from samples