Emicerfont (C007B-353304)

Emicerfont is a corticotropin-releasing factor type 1 ( CRF 1 ) receptor antagonist with an IC 50 of 66 nM.In VitroEmicerfont is a corticotropin-releasing factor type 1 (CRF 1 ) receptor antagonist with an IC 50 of 66 nM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.In VivoAt concentration of 10 mg/kg, Emicerfont reduces i.c.v. CRF-induced gerbil forepaw treading and marmoset defensive postures. Emicerfont also reduces rat pup ultrasonic vocalization at concentration of 30 mg/kg . MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:IC50: 66 nM (CRF 1 receptor).

Specifications and Purity: ≥98%

Molecular Formula: C22H24N6O2

Molecular Weight: 404.46

PubChem CID: 11223423

Isomeric SMILES: CC1=CC(=C2CCN(C2=N1)C3=C(C=C(C=C3)OC)C)N4C=CC(=N4)N5CCNC5=O