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egfr inhibitor

EGFR inhibitor (C007B-153421)

Catalog No.
C007B-153421
Manufacturer No.
E337818-100mg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA

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EGFR Inhibitor is a cell permeable compound that is a highly selective inhibitor of EGFR (epidermal growth factor receptor). Inhibition of EGFR has been shown to induce apoptosis. Mechanistic studies have shown that EGFR inhibition takes place via

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EGFR Inhibitor is a cell permeable compound that is a highly selective inhibitor of EGFR (epidermal growth factor receptor). Inhibition of EGFR has been shown to induce apoptosis. Mechanistic studies have shown that EGFR inhibition takes place via downregulation of antiapoptotic protein survivin expression. Downregulation of Survivin has been observed to take place following inhibition of the PI3K-AKT signaling pathway. Additional experiments report that EGFR inhibitors also induce upregulation of proapoptotic protein BIM.

Specifications and Purity: ≥98%

Molecular Formula: C21H18F3N5O

Molecular Weight: 413.4

PubChem CID: 9549299

Isomeric SMILES: C1CC1C(=O)NC2=CC=CC(=C2)NC3=NC=NC(=C3)NC4=CC=CC(=C4)C(F)(F)F

Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/E337818-SCI_96d3be2942a704a40ee09b56860d644f.pdf

UPC:
51131508
Condition:
New
HazmatClass:
No
WeightUOM:
LB
MPN:
E337818-100mg
CAS:
879127-07-8
Product Size:
100mg
Precautionary Statement Codes:
P264

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