DUB-IN-1 is an active inhibitor of ubiquitin-specific proteases (USPs) , with an IC 50 of 0.85 μM for USP8In VitroDUBs-IN-1 (22 d) is an active inhibitor of ubiquitin-specific proteases, with an IC 50 of 0.85 μM for USP8. DUBs-IN-1 is inactive toward USP7 (IC 50 , >100 μM). DUBs-IN-1 and its analogs reduce the viability of HCT116 colon and PC-3 prostate cancer cell lines with IC 50 s ranging from 0.5 μM to 1.5 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:IC50: 0.24 μM (USP8).
Specifications and Purity: ≥99%
Molecular Formula: C20H11N5O
Molecular Weight: 337.33
- UPC:
- 41106223
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- D650312-100mg
- CAS:
- 924296-18-4
- Product Size:
- 100mg
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