DS-7423 (C007B-349213)

Catalog No.: C007B-349213
Manufacturer No.: D656862-1ml
Manufacturer Name: Aladdin Scientific
Quantity: 1
Unit of Measure: EA

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Description
Specifications

DS-7423 is a dual PI3K and mTOR inhibitor, with IC 50 values of 15.6 nM, 34.9 nM for PI3Kα and mTOR , respectively. DS-7423 possesses anti-tumor activity.In VitroDS-7423 increases TP53 expression, the level of p-TP53 on Ser-46, and induced apoptosisrelated TP53 target genes (TP53AIP1 and PUMA) in OCCC cells. DS-7423 also inhibits other isoforms of class I PI3K (IC 50 values: PI3Kβ = 1,143 nM; PI3Kγ = 249 nM; PI3Kδ = 262 nM). MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Specifications and Purity: 10mM in DMSO

Molecular Formula: C22H27F3N10O2

Molecular Weight: 520.51

UPC:: 12141602
Condition:: New
HazmatClass:: No
WeightUOM:: LB
MPN:: D656862-1ml
CAS:: 1222104-37-1
Product Size:: 1ml

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