DS-1001b (DS 1001) (C007B-137229)

Catalog No.: C007B-137229
Manufacturer No.: D414241-100mg
Manufacturer Name: Aladdin Scientific
Quantity: 1
Unit of Measure: EA

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Description
Specifications

InformationDS-1001b (DS 1001) DS-1001b is an oral selective inhibitor of mutant IDH1 R132X with potential antineoplastic activity and is designed to penetrate the blood-brain barrier.TargetsIDH1 R132XIn vitroDS-1001b impairs the proliferation of IDH1 mutant chondrosarcoma cell lines and decreases 2-HG levels.In vivoContinuous administration of DS-1001b impairs tumor growth in xenograft mice.Cell Research(from reference)Cell lines：JJ012,L835 cell lines Concentrations：0-10µM Incubation Time：72 h.

Specifications and Purity: ≥98%

Molecular Formula: C29H29Cl3FN3O4

Molecular Weight: 608.92

PubChem CID: 139600317

Isomeric SMILES: CC1=CN(C2=CC=CC(=C12)/C=C/C(=O)O)C(=O)C3=C(ON=C3C4=C(C=C(C=C4Cl)Cl)Cl)C(C)(C)F.CC(C)(C)N

UPC:: 41106102
Condition:: New
HazmatClass:: No
WeightUOM:: LB
MPN:: D414241-100mg
CAS:: 1898207-64-1
Product Size:: 100mg

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