akash.verma@cenmed.com
(732) 447-1115-
14797-5An isothiocyanate derived from glucoraphanin powerful antioxidant, anti-inflammatory, and anti-carcinogenic effects at 40 µM, activates Nrf2-mediated gene expression of phase II detoxification enzymes by disrupting the Keap1-Nrf2 complex, -
10008618-10Lauric acid leelamide is the lauric (C-12) amide analog of leelamine. Leelamine has weak affinity for the human CB1 and CB2 receptors, exhibiting 20% displacement of [3H]-CP55940 at a concentration of 10 µM. -
14765-1Sulprostone is a metabolism resistant synthetic analog of PGE2. It is a selective agonist for EP3 receptors with a Ki value of 0. -
9002532-1A naturally occurring metabolite of bile acid that is produced by the conjugation of cholic acid and sulfate, predominantly in the liver and gut. -
16805-10An oxidized metabolite of sulindac that is produced in many mammals but minimally in mice and rats generally considered to be inactive against COX enzymes, although it can reduce azoxymethane-induced colon cancer in rats inhibits aldose reductase -
18468-5A sulfated bile acid that is used to induce pancreatic acinar cell injury in models of pancreatitis and to study bile acid transport. -
19521-1A naturally-occurring sterol and biosynthetic precursor of several animal, fungal, and protozoan steroids, including cholesterol and ergosterol. -
17275-10A hydrophobic bile acid formed in the liver by conjugation of lithocholate with taurine induces apoptosis in hepatocytes at 75 µM used to experimentally induce cholestasis. -
10008618-5Lauric acid leelamide is the lauric (C-12) amide analog of leelamine. Leelamine has weak affinity for the human CB1 and CB2 receptors, exhibiting 20% displacement of [3H]-CP55940 at a concentration of 10 µM. -
9002532-500A naturally occurring metabolite of bile acid that is produced by the conjugation of cholic acid and sulfate, predominantly in the liver and gut. -
16805-5An oxidized metabolite of sulindac that is produced in many mammals but minimally in mice and rats generally considered to be inactive against COX enzymes, although it can reduce azoxymethane-induced colon cancer in rats inhibits aldose reductase -
16098-1A major metabolite of sulforaphane that has been shown induce ARE-driven gene expression with roughly 8-fold less potency than sulforaphane.
