A tripeptide analog of glutathione that can selectively inhibit GSTP1-1 catalytic activity (Ki = 400 nM) with minimal effect on the related GST&alpha and -µ families (Kis range from 20-75 µM) restores JNK-mediated cellular
A tripeptide analog of glutathione that can selectively inhibit GSTP1-1 catalytic activity (Ki = 400 nM) with minimal effect on the related GST&alpha and -µ families (Kis range from 20-75 µM) restores JNK-mediated cellular
A potent inhibitor of PKC&beta (IC50 = 6 nM), with modest selectivity over PKC&alpha, &gamma, and &epsilon (IC50 = 39, 83, and 110 nM, respectively) at 3 µM, also inhibits signaling through the Akt pathway suppresses angiogenesis,
A potent inhibitor of PKC&beta (IC50 = 6 nM), with modest selectivity over PKC&alpha, &gamma, and &epsilon (IC50 = 39, 83, and 110 nM, respectively) at 3 µM, also inhibits signaling through the Akt pathway suppresses angiogenesis,
A potent inhibitor of PKC&beta (IC50 = 6 nM), with modest selectivity over PKC&alpha, &gamma, and &epsilon (IC50 = 39, 83, and 110 nM, respectively) at 3 µM, also inhibits signaling through the Akt pathway suppresses angiogenesis,
A potent inhibitor of PKC&beta (IC50 = 6 nM), with modest selectivity over PKC&alpha, &gamma, and &epsilon (IC50 = 39, 83, and 110 nM, respectively) at 3 µM, also inhibits signaling through the Akt pathway suppresses angiogenesis,
A potent inhibitor of PKC&beta (IC50 = 6 nM), with modest selectivity over PKC&alpha, &gamma, and &epsilon (IC50 = 39, 83, and 110 nM, respectively) at 3 µM, also inhibits signaling through the Akt pathway suppresses angiogenesis,
A potent inhibitor of PKC&beta (IC50 = 6 nM), with modest selectivity over PKC&alpha, &gamma, and &epsilon (IC50 = 39, 83, and 110 nM, respectively) at 3 µM, also inhibits signaling through the Akt pathway suppresses angiogenesis,
A tripeptide analog of glutathione that can selectively inhibit GSTP1-1 catalytic activity (Ki = 400 nM) with minimal effect on the related GST&alpha and -µ families (Kis range from 20-75 µM) restores JNK-mediated cellular
A tripeptide analog of glutathione that can selectively inhibit GSTP1-1 catalytic activity (Ki = 400 nM) with minimal effect on the related GST&alpha and -µ families (Kis range from 20-75 µM) restores JNK-mediated cellular