Sodium thiosalicylate

An inhibitor of &beta-lactamases with greater activity against Ambler class A serine penicillinases and class C cephalosporinases, including TEM-1, SHV-1, and P99 (IC₅₀s = 97, 150, and 8.5 nM) also inhibits the class D oxacillinase

A cell-permeable diarylurea compound that inhibits apoptosome formation and caspase activation blocks cytochrome c-induced caspase activation in HeLa cell cytosolic extracts with an IC₅₀ value of approximately 50 &microM suppresses

Thioarginine (hydrobromide) is a colorimetric substrate for arginase that provides the basis for continuous spectrophotometric measurement of enzyme activity. It exhibits Km and kcat values of 0.

A carnitine ester that inhibits carnitine-acylcarnitine translocase (IC₅₀ = 33 &muM).

A potent and selective competitive inhibitor of nNOS (Ki = 57 nM bovine) exhibits 3,000-fold and 150-fold selectivity for the neuronal isoform versus the inducible (murine Ki = 180 &microM) and endothelial (bovine Ki = 8.5 &microM) isoforms of

A thio analog of the purine base guanine that incorporates into DNA during replication, inducing double-strand breaks that destabilize its structure and result in cytotoxicity used as a chemotherapeutic for acute leukemia and other types of cancer,

A phospholipid containing palimitoyl (16:0) and oleoyl (18:1) acyl substituents at the sn-1 and sn-2 positions, respectively, that been used to generate lipid membrane bilayers with controlled permeability and may be useful for various surfactant

3-thia TDA is an analog of the 14-carbon saturated fatty acid myristic acid, wherein the C-3 carbon has been replaced by sulfur in a thioether linkage. When chronically administered to rats, 3-thia TDA acts as a peroxisome inducer (PPAR ligand),

A dual MET/AXL inhibitor.

A colorimetric substrate for KIAA1363, a 2-acetyl monoacylglyceryl ether hydrolase critical to the survival and proliferation of many cancer cell lines.

An anti-migraine agent.

A serine proteases inhibitor that is capable of inhibiting trypsin (a digestive system protease Ki = 15 nM), tryptase (a mast cell protease Ki = 95.3 pM), and additional proteases in the coagulation cascade including thrombin (Ki = 0.