A thio analog of the purine base guanine that incorporates into DNA during replication, inducing double-strand breaks that destabilize its structure and result in cytotoxicity; used as a chemotherapeutic for acute leukemia and other types of cancer, including BRCA2-mutated tumors.
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- UPC:
- 51142014
- HazmatClass:
- Yes
- WeightUOM:
- LB
- MPN:
- 15774-500
- CAS:
- 154-42-7
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