Estramustine

A hydroxylated metabolite of estrone as well as an interconversion product with estriol formed by CYP1A1, CYP3A5, CYP3A4, and CYP3A7 binds covalently and persistently activates estrogen receptors increases cell proliferation and does not suppress

cis-4,10-13,16-Docosatetraenoic acid methyl ester is a long chain PUFA. It is a minor fatty acid component of rat testis lipids. The methyl ester is a neutral, more lipophilic form of the free acid.

A selective FAAH inhibitor (IC50 = 5.25 nM in rat brain homogenates) with potential analgesic and anxiolytic activity does not inhibit acidic PEAase or bind to CB1 or CB2 receptors.

One of serveral novel taurine-conjugated fatty acids that act as a FAAH substrate and may activate TRPV1 and TRPV4.

An endogenous lipid that has been reported to stimulate bone formation and to inhibit bone resorption.

Estrone is one of the three naturally occurring estrogens, the others being estradiol and estriol. Estrone is synthesized from androstenedione by the aromatase enzyme system in the ovaries and placenta, and is also synthesized from estradiol by

A stable analog of PGE2 2-glyceryl ester.

A selective FAAH inhibitor (IC50 = 5.25 nM in rat brain homogenates) with potential analgesic and anxiolytic activity does not inhibit acidic PEAase or bind to CB1 or CB2 receptors.

Unoprostone isopropyl ester (Rescula) is the clinically approved, prodrug form of unoprostone, which is a free acid analog of PGF2&alpha. Both latanoprost and Rescula have been approved for the treatment of ocular hypertension.

A potential trace impurity in commercial preparations of latanoprost.

PGE2 p-benzamidophenyl ester is a crystalline derivative of PGE2. PGE2 is one of the primary COX products of arachidonic acid and one of the most widely investigated prostaglandins.

An estradiol analog that binds to ER&alpha with IC50 values in the range of 22-28 nM