BIRB 796 (Doramapimod) is a highly selective p38α MAPK inhibitor with Kd of 0.1 nM, 330-fold greater selectivity versus JNK2, weak inhibition for c-RAF, Fyn and Lck, insignificant inhibition of ERK-1, SYK, IKK2, ZAP-70, EGFR, HER2, PKA, PKC, PKCα/β/γ.A p38α MAPK and JNK2;p38 MAPK抑制剂.
Specifications and Purity: ≥99%
Molecular Formula: C31H37N5O3
Molecular Weight: 527.67
PubChem CID: 156422
Isomeric SMILES: CC1=CC=C(C=C1)N2C(=CC(=N2)C(C)(C)C)NC(=O)NC3=CC=C(C4=CC=CC=C43)OCCN5CCOCC5
Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/D125100-SCI_aa70a2f511e66601c8420b9050408139.pdf
- UPC:
- 10161824
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- D125100-250mg
- CAS:
- 285983-48-4
- Product Size:
- 250mg
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