DNA-PK Inhibitor V is a morpholino-benzophenone compound. Potent, selective and ATP-competitive inhibitor of DNA-PK (IC|50|= 270 nM). Inhibits PI 3-K catalytic subunit p110-isozymes at higher concentrations (IC|50|= 32 μM, 3.7 μM, 22 μM and ~ 100μM for α, β, δ and γ, respectively) and weakly inhibits a panel of several other kinases, including, ATM, ATR, CK2, GRK2, mTOR, PI 3KC2α, PI 3KC2β, PI 3KC2γ and PI 4Kβ, even at concentrations as high as 50μM.
Specifications and Purity: ≥98%
Molecular Formula: C17H17NO3
Molecular Weight: 283.32
PubChem CID: 16760391
Isomeric SMILES: C1COCCN1C2=CC(=C(C=C2)C(=O)C3=CC=CC=C3)O
Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/D337627-SCI_69ae1b519ee49b31913508e4871f5f9d.pdf
- UPC:
- 51182010
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- D337627-1mg
- CAS:
- 404009-46-7
- Product Size:
- 1mg
- Precautionary Statement Codes:
- P264
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