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DNA Methylation ELISA Kit-480 Well

DNA Methylation ELISA Kit-480 Well

Catalog No.
C003B-388766
Manufacturer No.
589324-480
Manufacturer Name
CAYMAN CHEMICAL
Quantity
1
Unit of Measure
EA

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DNA methylation is an important epigenetic process regulating gene expression. Methylation occurs on carbon 5 of 2-deoxy cytidine yielding the modified base 5-methyl-2-deoxy cytidine.

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DNA methylation is an important epigenetic process regulating gene expression. Methylation occurs on carbon 5 of 2-deoxy cytidine yielding the modified base 5-methyl-2-deoxy cytidine. The methylation pattern of cells is tightly regulated during development with the methylation profile being transmitted from parent to daughter cells during cell division. Methylation results in long-term silencing of genes, while unmethylated regions of DNA can be actively transcribed. Cayman’s DNA Methylation ELISA is a competitive assay that can be used for quantification of 5-methyl-2-deoxy cytidine in urine, culture supernatants, plasma, and other sample matrices. The ELISA typically displays IC50 (50% B/B0) and IC80 (B/B0) values of approximately 12 and 3 ng/ml, respectively.

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UPC:
41106100
HazmatClass:
Yes
WeightUOM:
LB
MPN:
589324-480

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