DMT-DC(BZ) AMIDITE 5G SINGLE (C005B-004393)

General description

Proligo′s DNA phosphoramidites lead to high-yield and high-quality oligonucleotides due to their high coupling efficiency. The deprotection step of automated oligonucleotide synthesis is integral to synthesis time and final product quality. Exocyclic amine functions are protected by a benzoyl group (dA(bz) and dC(bz)) or isobutyryl group (dG(ib))Key features of DNA phosphoramidites :

• Recommended cleavage and deprotection conditions are 8 hours at 55 °Cor 24 hours at room temperature using concentrated ammonia solution,for standard base-protected oligonucleotides
• The high coupling efficiency of Proligo′s DNA phosphoramidites leads tohigh-yield and high-quality oligonucleotides

The product belongs to ÄKTA® synthesizers.

Legal Information

OligoPilot is a registered trademark of Cytiva

ÄKTA is a registered trademark of Cytiva

Molecular Weight: 833.91. Empirical Formula: C₄₆H₅₂N₅O₈P. biological source: non-animal source (no BSE/TSE risk). Quality Level: 200. type: for DNA synthesis. product line: Proligo Reagents. Assay: ≥. 99% (³¹P-NMR), ≥. 99.0% (reversed phase HPLC). form: powder or granules. technique(s): oligo synthesis: suitable. impurities: ≤. 0.3 . wt. % water content (Karl Fischer). color: white to off-white. λ: conforms (UV/VIS Identity). compatibility: configured for (ÄKTA^®. and OligoPilot^®. ), configured for ABI. nucleoside profile: base: deoxycytidine
base protecting group: benzoyl
2' protecting group: none
5' protecting group: DMT
deprotection: standard. storage temp.: 2-8°C. SMILES string: COc1ccc(cc1)C(OC[C@H]2O[C@H](C[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)N3C: CC(NC(: O)c4ccccc4): NC3: O)(c5ccccc5)c6ccc(OC)cc6. InChI: 1S/C46H52N5O8P/c1-32(2)51(33(3)4)60(57-29-13-27-47)59-40-30-43(50-28-26-42(49-45(50)53)48-44(52)34-14-9-7-10-15-34)58-41(40)31-56-46(35-16-11-8-12-17-35,36-18-22-38(54-5)23-19-36)37-20-24-39(55-6)25-21-37/h7-12,14-26,28,32-33,40-41,43H,13,29-31H2,1-6H3,(H,48,49,52,53)/t40-,41+,43+,60?/m0/s1. InChI key: PGTNFMKLGRFZDX-SALLYJDFSA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.