General description
Proligo′s DNA phosphoramidites lead to high-yield and high-quality oligonucleotides due to their high coupling efficiency. The deprotection step of automated oligonucleotide synthesis is integral to synthesis time and final product quality. Exocyclic amine functions are protected by a benzoyl group (dA(bz) and dC(bz)) or isobutyryl group (dG(ib))Key features of DNA phosphoramidites :
- Recommended cleavage and deprotection conditions are 8 hours at 55 °Cor 24 hours at room temperature using concentrated ammonia solution,for standard base-protected oligonucleotides
- The high coupling efficiency of Proligo′s DNA phosphoramidites leads tohigh-yield and high-quality oligonucleotides
Packaging
C111040-1G packaged in a 1 oz bottle with a 28-400 cap
C111040-10G packaged in a 8 oz bottle with a 28-400 cap
C111040-6x5G packaged in a 8 oz bottle with a 28-400 cap
C111040-6x10G packaged in a 8 oz bottle with a 28-400 cap
C111040-20x10G packaged in a 1 L bottle with GL 45
base protecting group: benzoyl
2' protecting group: none
5' protecting group: DMT
deprotection: standard. storage temp.: 2-8°C. SMILES string: COc1ccc(cc1)C(OC[C@H]2O[C@H](C[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)N3C: CC(NC(: O)c4ccccc4): NC3: O)(c5ccccc5)c6ccc(OC)cc6. InChI: 1S/C46H52N5O8P/c1-32(2)51(33(3)4)60(57-29-13-27-47)59-40-30-43(50-28-26-42(49-45(50)53)48-44(52)34-14-9-7-10-15-34)58-41(40)31-56-46(35-16-11-8-12-17-35,36-18-22-38(54-5)23-19-36)37-20-24-39(55-6)25-21-37/h7-12,14-26,28,32-33,40-41,43H,13,29-31H2,1-6H3,(H,48,49,52,53)/t40-,41+,43+,60?/m0/s1. InChI key: PGTNFMKLGRFZDX-SALLYJDFSA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.
- UPC:
- 41105332
- Condition:
- New
- HazmatClass:
- Yes
- MPN:
- C111040-20X10G
- CAS:
- 102212-98-6
akash.verma@cenmed.com
(732) 447-1115





