DMT-DA(BZ) AMIDITE 10G SINGLE (C005B-092302)

General description

Proligo′s DNA phosphoramidites lead to high-yield and high-quality oligonucleotides due to their high coupling efficiency. The deprotection step of automated oligonucleotide synthesis is integral to synthesis time and final product quality. Exocyclic amine functions are protected by a benzoyl group (dA(bz) and dC(bz)) or isobutyryl group (dG(ib)).Key features of DNA phosphoramidite :

• Recommended cleavage and deprotection conditions are 8 hours at 55 °Cor 24 hours at room temperature using concentrated ammonia solution, for standard base-protected oligonucleotides
• The high coupling efficiency of Proligo′s DNA phosphoramidites leads to high-yield and high-quality oligonucleotides. The product belongs to ABI Synthesizers synthesizers.

Legal Information

OligoPilot is a registered trademark of Cytiva

ÄKTA is a registered trademark of Cytiva

Molecular Weight: 857.93. Empirical Formula: C₄₇H₅₂N₇O₇P. biological source: non-animal source (no BSE/TSE risk). Quality Level: 200. type: for DNA synthesis. product line: Proligo Reagents. Assay: ≥. 99% (³¹P-NMR), ≥. 99.0% (reversed phase HPLC). form: powder or granules. technique(s): oligo synthesis: suitable. impurities: ≤. 0.3 . wt. % water content (Karl Fischer). color: white to off-white. λ: conforms (UV/VIS Identity). compatibility: configured for ÄKTA^®. and OligoPilot^®. . nucleoside profile: base: deoxyadenosine
base protecting group: benzoyl
2' protecting group: none
5' protecting group: DMT
deprotection: standard. storage temp.: 2-8°C. SMILES string: COc1ccc(cc1)C(OC[C@H]2O[C@H](C[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)n3cnc4c(NC(: O)c5ccccc5)ncnc34)(c6ccccc6)c7ccc(OC)cc7. InChI: 1S/C47H52N7O7P/c1-32(2)54(33(3)4)62(59-27-13-26-48)61-40-28-42(53-31-51-43-44(49-30-50-45(43)53)52-46(55)34-14-9-7-10-15-34)60-41(40)29-58-47(35-16-11-8-12-17-35,36-18-22-38(56-5)23-19-36)37-20-24-39(57-6)25-21-37/h7-12,14-25,30-33,40-42H,13,27-29H2,1-6H3,(H,49,50,52,55)/t40-,41+,42+,62?/m0/s1. InChI key: GGDNKEQZFSTIMJ-AKWFTNRHSA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.