DMOTY

Application

DMOTY TEA is a thiacyanine-based fluorescent autophagy probe that localizes to lysosomes of live cells via selective binding to G-quadruplexes. DMOTY TEA will be a valuable tool for probing autophagy mechanisms and drug discovery research centering on protein degradation.

Other Notes

Monitoring autophagy in live cells with a fluorescent light-up probe for G-quadruplex structures

Molecular Weight: 686.90. Empirical Formula: C₂₉H₄₀N₃O₈S₄. Quality Level: 100. Assay: ≥. 95%. form: powder. storage temp.: −. 20°C. SMILES string: COC1: CC: C2C(N(C(S2): CC3: [N+](CCCS(: O)([O-]): O)C(C: C(OC)C: C4): C4S3)CCCS(: O)([O-]): O): C1.CCN(CC)CC. InChI: 1S/C23H26N2O8S4.C6H15N/c1-32-16-5-7-20-18(13-16)24(9-3-11-36(26,27)28)22(34-20)15-23-25(10-4-12-37(29,30)31)19-14-17(33-2)6-8-21(19)35-23. 1-4-7(5-2)6-3/h5-8,13-15H,3-4,9-12H2,1-2H3,(H-,26,27,28,29,30,31). 4-6H2,1-3H3. InChI key: XGDLAZBMOHDWKV-UHFFFAOYSA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.