Diphyllin is an arylnaphthalene lignan isolated from Justicia procumbens and is a potent HIV-1 inhibitor with an IC50 of 0.38 μM. Diphyllin is active against vesicular stomatitis virus (VSV) and influenza virus. Diphyllin is a vacuolar type H+-ATPase (V-ATPase) inhibitor with an IC50 value of 17 nM and inhibits lysosomal acidification in human osteoclasts. Diphyllin inhibits NO production with an IC50 of 50 μM and has anticancer and anti-inflammatory activities.
Specifictaions: Moligand™, ≥99%
MDL Number: C21H16O7
Molecular Formula: 380.35
PubChem CID: 100492
Isomeric SMILES: COC1=C(C=C2C(=C1)C(=C3C(=C2O)COC3=O)C4=CC5=C(C=C4)OCO5)OC
- UPC:
- 51161513
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- D648196-1mg
- CAS:
- 22055-22-7
- Product Size:
- 1mg
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