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diethyl-pythidc (c09-1126-632)

Diethyl-pythiDC (C007B-349117)

Catalog No.
C007B-349117
Manufacturer No.
D655151-1ml
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA

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Diethyl-pythiDC is an inhibitor of collagen prolyl 4-hydroxylases (CP4Hs).In VitroDiethyl-pythiDC inhibits CP4H activity in cultured cells at concentrations that do not cause iron deficiency. MDA-MB-231 cells are treated with biheteroaryl

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Diethyl-pythiDC is an inhibitor of collagen prolyl 4-hydroxylases (CP4Hs).In VitroDiethyl-pythiDC inhibits CP4H activity in cultured cells at concentrations that do not cause iron deficiency. MDA-MB-231 cells are treated with biheteroaryl dicarboxylates, and assayed for cytotoxicity and indicators of iron deficiency. None of the esterified biheteroaryl dicarboxylates exhibited cytotoxic activity at high micromolar concentrations. Cells treated with dihydroxybenzoate (EDHB demonstrate a strong iron-deficient phenotype. In contrast, cells treated with Diethyl-pythiDC (Diethyl pythiDC) appear to be normal at concentrations as high as 500 μM. Treatment with Diethyl-pythiDC and low levels of diethyl pyimDC does not affect the level of TfR, HIF-1α, or ferritin. MCE has not independently confirmed the accuracy of these methods. They are for reference only.IC50& Target:CP4H.

Specifications and Purity: 10mM in DMSO

Molecular Formula: C14H14N2O4S

Molecular Weight: 306.34

UPC:
10191511
Condition:
New
HazmatClass:
No
WeightUOM:
LB
MPN:
D655151-1ml
CAS:
1821370-70-0
Product Size:
1ml

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