Diethyl Pyrocarbonate has been shown to inhibit ryanodine binding to ryanodine/Ca2+ receptor channels in skeletal muscle in a dose- and time-dependent manner and increases the Ca2+ permeability of SR vesicles. This compound could be useful for specific inactivation of nucleases during isolation of undegraded polynucleotides. Diethyl Pyrocarbonate also inhibits PAF Acetylhydrolase (platelet-activating factor acetyl hydrolase), and has been used as a probe for the topography of 5.8S rRNA in yeast ribosomes.An inhibitor of ryanodine binding at the ryanodine/Ca2+ channel.
Specifications and Purity: ≥97%
MDL Number: MFCD00009106
Molecular Formula: C6H10O5
Molecular Weight: 162.14
EC Number: 216-542-8
PubChem CID: 3051
Isomeric SMILES: CCOC(=O)OC(=O)OCC
Beilstein Registry Number: 637031
Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/D137738-SCI_ce7e0cd3539850856cf641fb39e832f6.pdf
- UPC:
- 12141909
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- D137738-500g
- CAS:
- 1609-47-8
- Product Size:
- 500g
- Hazard Statement Codes:
- H335:H319:H315:H302
- Precautionary Statement Codes:
- P305+P351+P338:P261
akash.verma@cenmed.com
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