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dichloromethylenediphosphonic acid disodium salt

DICHLOROMETHYLENEDIPHOSPHONIC ACID SODIUM SALT

Catalog No.
C005B-026149
Manufacturer No.
D4434-1G
Manufacturer Name
Sigma-Aldrich
Quantity
1
Unit of Measure
GR

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Biochem/physiol Actions Analog of pyrophosphate ion that inhibits the osteoclastic activity leading to bone resorption and osteoporosis. The compound is used in cancer research, especially in skeletal metastases and breast carcinoma.

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Biochem/physiol Actions

Analog of pyrophosphate ion that inhibits the osteoclastic activity leading to bone resorption and osteoporosis. The compound is used in cancer research, especially in skeletal metastases and breast carcinoma. When entrapped in liposomes, it is used for macrophage-selective depletion (macrophage "suicide" technique), especially in spleen and liver. Found also to inhibit collagenase and matrix metalloproteinase1.

Molecular Weight: 288.86. Empirical Formula: CH2Cl2Na2O6P2. linearFormula: CH2O6Cl2Na2P2. form: powder. Quality Level: 300. solubility: water: 49.00-51.00 . mg/mL, clear, colorless. storage temp.: room temp. SMILES string: [Na+].[Na+].OP([O-])(: O)C(Cl)(Cl)P(O)([O-]): O. InChI: 1S/CH4Cl2O6P2.2Na/c2-1(3,10(4,5)6)11(7,8)9. . /h(H2,4,5,6)(H2,7,8,9). . /q. 2*+1/p-2. InChI key: HJKBJIYDJLVSAO-UHFFFAOYSA-L. Gene Information: rat ... Man2a1(25478), Si(497756). Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).
UPC:
51182416
Condition:
New
HazmatClass:
No
MPN:
D4434-1G
CAS:
22560-50-5

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