Diallyl N,N-diisopropylphosphoramidite (C007B-133933)

Precursor involved in the synthesis of pharmacologically active molecules including:Selective orally active S1P1 agonistsWater-soluble prodrugs of triazole CS-758 with antifungal activityFostriecin analogs as antitumor agentsReactant involved in:Phosphitylation of alcoholsDeallylation for the synthesis of nucleoside phosphoramiditePosphitylation and stereoselective Pudovik rearrangementDiallyl N,N-diisopropylphosphoramidite may be employed as phophorylating reagent in the following studies:Preparation of peptide substrates.Preparation of rhodamine dyes with phosphorylated CH2OH sites.Synthesis of 3-[4-(bis-allyloxy-phosphoryloxy)-2(R)-hydroxy-3,3-dimethyl-butyrylamino]-thiopropionic acid-S-propylester.

Specifications and Purity: ≥90%

Molecular Formula: C12H24NO2P

Molecular Weight: 245.3

PubChem CID: 4686855

Isomeric SMILES: CC(C)N(C(C)C)P(OCC=C)OCC=C

Beilstein Registry Number: 4383514

Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/D332864-SCI_6f866a5f1a4b98c1cffb5fa4c3e1baf7.pdf