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dextromethorphan hydrobromide monohydrate (c15-1256-679)

DEXTROMETHORPHAN HYDROBROMIDE: MONOHYDRATE (C005B-056106)

Catalog No.
C005B-056106
Manufacturer No.
D2531-10G
Manufacturer Name
Sigma-Aldrich
Quantity
10
Unit of Measure
GR

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Application Dextromethorphan hydrobromide monohydrate has been used as a substrate for cytochrome P450 2D6 enzyme action, in potassium phosphate buffer for measuring P450 activity and is used in enzyme inhibition studies. Biochem/physiol Actions

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Application

Dextromethorphan hydrobromide monohydrate has been used as a substrate for cytochrome P450 2D6 enzyme action, in potassium phosphate buffer for measuring P450 activity and is used in enzyme inhibition studies.

Biochem/physiol Actions

Dextromethorphan hydrobromide is an allosteric antagonist at N-methyl D- aspartate (NMDA)-controlled ion channels and antagonist at voltage-dependent channels. Dextromethorphan hydrobromide is useful in treating dry cough.

Molecular Weight: 370.32. Empirical Formula: C18H25NO · HBr · H2O. Quality Level: 200. Assay: ≥. 99% (TLC). form: powder. SMILES string: Br[H].[H]O[H].[H][C@]12CCCC[C@]13CCN(C)[C@H]2Cc4ccc(OC)cc34. InChI: 1S/C18H25NO.BrH.H2O/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18. . /h6-7,12,15,17H,3-5,8-11H2,1-2H3. 1H. 1H2/t15-,17+,18+. . /m1../s1. InChI key: STTADZBLEUMJRG-IKNOHUQMSA-N. Gene Information: human ... GRIN1(2902), GRIN2A(2903), GRIN2B(2904), GRIN2C(2905), GRIN2D(2906), GRIN3A(116443), GRIN3B(116444), SIGMAR1(10280). Pictograms: GHS06,GHS09. Signal Word: Danger. Hazard Statements: H301 - H411. Precautionary Statements: P264 - P270 - P273 - P301 + P310 - P391 - P405. Hazard Classifications: Acute Tox. 3 Oral - Aquatic Chronic 2. Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects. WGK: WGK 2. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).
UPC:
51111606
Condition:
New
HazmatClass:
Yes
MPN:
D2531-10G
CAS:
6700-34-1

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