DEXAMETHASON VETRANAL 250 MG (C005B-044796)

General description

Dexamethasone is a synthetic glucocorticoid and cortisol analogue. It is used in the suppression of adrenocorticotropic hormone (ACTH) and cortisol production in normal subjects.

Application

Dexamethasone may be used as a reference standard in the determination of dexamethasone in biological samples using high-performance liquid chromatography (HPLC).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase.

Legal Information

VETRANAL is a registered trademark of Sigma-Aldrich Chemie GmbH

Molecular Weight: 392.46. Empirical Formula: C₂₂H₂₉FO₅. grade: analytical standard. Quality Level: 100. product line: VETRANAL^®. . shelf life: limited shelf life, expiry date on the label. technique(s): HPLC: suitable, gas chromatography (GC): suitable. mp: 262-264 . °C (lit.). application(s): clinical. format: neat. storage temp.: 2-8°C. SMILES string: C[C@@H]1C[C@H]2[C@@H]3CCC4: CC(: O)C: C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(: O)CO. InChI: 1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1. InChI key: UREBDLICKHMUKA-CXSFZGCWSA-N. Gene Information: human ... NR3C1(2908). Pictograms: GHS08. Signal Word: Danger. Hazard Statements: H360FD. Precautionary Statements: P201 - P202 - P280 - P308 + P313 - P405 - P501. Hazard Classifications: Repr. 1B. Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves.