DEXAMETHASONE 21-ACETATE (C005B-010424)

Application

Dexamethasone 21-acetate has been used:

• as a component of the induction medium for the treatment of mice preadipocytes (5A) cells
• as a synthetic glucocorticoid to study its effects on the expression of nuclear factor erythroid 2-related factor 2 (Nrf2) and peroxiredoxin 6 (Prdx6) proteins in placentas of human and mice
• as a component of the complete medium for the culturing of porcine hepatocytes

Biochem/physiol Actions

Dexamethasone 21-acetate or dexamethasone acetate is a derivative of dexamethasone. It is a hydrophobic drug. Dexamethasone is a glucocorticoid possessing anti-inflammatory activity.

Molecular Weight: 434.50. Empirical Formula: C₂₄H₃₁FO₆. Quality Level: 100. Assay: ≥. 99%. form: powder. storage temp.: 2-8°C. SMILES string: [H][C@@]12CCC3: CC(: O)C: C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@@H](C)[C@]4(O)C(: O)COC(C): O. InChI: 1S/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17+,18+,19+,21+,22+,23+,24+/m1/s1. InChI key: AKUJBENLRBOFTD-RPRRAYFGSA-N. Gene Information: human ... NR3C1(2908). Pictograms: GHS08. Signal Word: Danger. Hazard Statements: H360FD. Precautionary Statements: P201 - P202 - P280 - P308 + P313 - P405 - P501. Hazard Classifications: Repr. 1B. Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects. WGK: WGK 3. Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves.