Desloratadine (C007B-123159)

Desloratadine is a potent and selective histamine H1-receptor agonist with a half life of 21-24 hours. Experiments suggest that this compound also exerts antioxidant effects in vitro. Other studies show that H1-receptor binding by desloratadine is reversible and that, over time, desloratadine dissociates from membrane H1-recepters. Desloratadine has also demonstrated the ability to block ICAM-1 upregulation and NFκB activation in primary bronchial and transformed respiratory epithelial cells in vitro.It is a potent antagonist for human histamine H1 receptor used to treat allergies.

Specifications and Purity: ≥98%(HPLC)(T)

MDL Number: MFCD00871949

Molecular Formula: C19H19ClN2

Molecular Weight: 310.83

PubChem CID: 124087

Isomeric SMILES: C1CC2=C(C=CC(=C2)Cl)C(=C3CCNCC3)C4=C1C=CC=N4

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