DES-ARG9 (LEU8)-BRADYKININ ACETATE

Amino Acid Sequence

Arg-Pro-Pro-Gly-Phe-Ser-Pro-Leu

Application

The Bradkykinin amid peptide des-Arg9-[Leu8]-Bradykinin is used as a bradykinin-1 receptor (B1R) antagonist frequently in comparison with the B1 receptor agonist des-Arg9-bradykinin.

Biochem/physiol Actions

Bradykinin receptor antagonist.

Molecular Weight: 870.01. Empirical Formula: C₄₁H₆₃N₁₁O₁₀. Quality Level: 200. Assay: ≥. 97% (HPLC). form: powder. color: white. storage temp.: −. 20°C. SMILES string: CC(O): O.CC(C)C[C@H](NC(: O)[C@@H]1CCCN1C(: O)[C@H](CO)NC(: O)[C@H](Cc2ccccc2)NC(: O)CNC(: O)[C@@H]3CCCN3C(: O)[C@@H]4CCCN4C(: O)[C@@H](N)CCCNC(N): N)C(O): O. InChI: 1S/C41H63N11O10.C2H4O2/c1-24(2)20-28(40(61)62)48-36(57)31-14-8-17-50(31)38(59)29(23-53)49-34(55)27(21-25-10-4-3-5-11-25)47-33(54)22-46-35(56)30-13-7-18-51(30)39(60)32-15-9-19-52(32)37(58)26(42)12-6-16-45-41(43)44. 1-2(3)4/h3-5,10-11,24,26-32,53H,6-9,12-23,42H2,1-2H3,(H,46,56)(H,47,54)(H,48,57)(H,49,55)(H,61,62)(H4,43,44,45). 1H3,(H,3,4)/t26-,27-,28-,29-,30-,31-,32-. /m0./s1. InChI key: XBFMNOKHQZCARQ-XXZMQFNDSA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).