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ddms

DDMS (C007B-134688)

Catalog No.
C007B-134688
Manufacturer No.
D344397-25mg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA

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DDMS is a mechanism-based, irreversible inhibitor that has about 10-fold selectivity for the CYP4A11 (CYP450 4A2) enzyme which predominantly synthesizes 20-HETE in the mammalian kidney. DDMS administration in whole anesthetized rats (10 mg/kg)

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DDMS is a mechanism-based, irreversible inhibitor that has about 10-fold selectivity for the CYP4A11 (CYP450 4A2) enzyme which predominantly synthesizes 20-HETE in the mammalian kidney. DDMS administration in whole anesthetized rats (10 mg/kg) largely ablates the hypotension and vasodilation induced by nitric oxide donors such as NONOates. Biosynthesis of 20-HETE from arachidonic acid by the CYP4A11 (cytochrome P450 4A) isoforms is an important component of vascular homeostasis, especially in renal circulation.

Specifications and Purity: ≥98%

Molecular Formula: C13H23Br2NO3S

Molecular Weight: 433.2

PubChem CID: 11212661

Isomeric SMILES: CS(=O)(=O)NC(=O)CCCCCCCCCC=C(Br)Br

Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/D344397-SCI_5e40523e424ebcb28a105360d7446631.pdf

UPC:
41111917
Condition:
New
HazmatClass:
No
WeightUOM:
LB
MPN:
D344397-25mg
CAS:
206052-03-1
Product Size:
25mg
Precautionary Statement Codes:
P264

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