DBEQ (C005B-313883)

Catalog No.: C005B-313883
Manufacturer No.: SML0031-25MG
Manufacturer Name: Sigma-Aldrich
Quantity: 25
Unit of Measure: MG

Application HeLa cells were treated with DBeQ and the effects on in vivo ubiquitination and protein dislocation were studied by live cell imaging. Biochem/physiol Actions DBeQ is a potent and specific inhibitor of ATPase p97, an integral

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Description
Specifications

Application

HeLa cells were treated with DBeQ and the effects on in vivo ubiquitination and protein dislocation were studied by live cell imaging.

Biochem/physiol Actions

DBeQ is a potent and specific inhibitor of ATPase p97, an integral component of the ubiquitin-fusion degradation (UFD) pathway. DBeQ inhibits the degradation of ubiquitinated proteins, the endoplasmic reticulum-associated degradation pathway, and autophagosome maturation. The compound also potently inhibits cellular proliferation and induces caspase 3/7 activity and apoptosis.

UPC:: 85111511
Condition:: New
HazmatClass:: No
MPN:: SML0031-25MG

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