Dabrafenib (GSK2118436) is a mutant BRAFV600 specific inhibitor with IC50 of 0.8 nM in cell-free assays, with 4- and 6-fold less potency against B-Raf(wt) and c-Raf, respectively.A potent and selective inhibitor of Raf-B protein kinase carrying V600E mutation.
Specifications and Purity: ≥98%
Molecular Formula: C23H20F3N5O2S2
Molecular Weight: 519.56
PubChem CID: 44462760
Isomeric SMILES: CC(C)(C)C1=NC(=C(S1)C2=NC(=NC=C2)N)C3=C(C(=CC=C3)NS(=O)(=O)C4=C(C=CC=C4F)F)F
Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/D127289-SCI_14a778b086957f8339ea9a4d910481b0.pdf
- UPC:
- 51111703
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- D127289-25mg
- CAS:
- 1195765-45-7
- Product Size:
- 25mg
- Hazard Statement Codes:
- H411:H400:H373:H361
- Precautionary Statement Codes:
- P501:P405:P391:P280:P273:P260
akash.verma@cenmed.com
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