D-Serine (C007B-261044)

D-serine has been used as a substrate in D-amino acid oxidase (DAO) activity in human 1321N1 astrocytoma cells. It has also been used in intracerebroventricular administration in rat for the induction of antinociceptive effect.D-serine has been used to prevent glycine-dependent desensitization of N-methyl D-aspartate receptor (NMDAR) and to study its effects on NMDARs to correct behavioral abnormalities in rats after partial sciatic nerve ligation (PSNL)product description：D-serine is an unusual amino acid expressed in the mammalian brain.D-serine is a dextro amino acid present in neurons, astrocytes, and microglia. It is synthesized from L-serine by the enzyme serine racemase. Racemase also catalyzes the breakdown of D-serine into ammonia and pyruvate. It is oxidized to hydroxypyruvate by D-amino acid oxidase.application：D-Serine is involved in the biosynthesis of purines, pyrimidines, and other amino acids. D-Serine also is an agonist of glycine site of the NMDA-type glutamate receptor. It also acts as Lacosamide intermediate.

Specifications and Purity: ≥98.5%

MDL Number: MFCD00004269

Molecular Formula: C3H7NO3

Molecular Weight: 105.09

EC Number: 206-229-4

PubChem CID: 71077

Isomeric SMILES: C([C@H](C(=O)O)N)O

Beilstein Registry Number: 1721403

Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/S105977-SCI_f3d7e289c8a93487c5ca9f787a09caab.pdf