CYM-5520 (C005B-312660)

Catalog No.: C005B-312660
Manufacturer No.: SML1014-25MG
Manufacturer Name: Sigma-Aldrich
Quantity: 25
Unit of Measure: MG

Application CYM-5520 has been used as a sphingosine 1-phosphate receptor 2 (S1pr2) agonist in pancreatic adenocarcinoma :cell :line (CFPAC-1). Biochem/physiol Actions CYM-5520 is a specific, noncompetitive allosteric agonist of

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Description
Specifications

Application

CYM-5520 has been used as a sphingosine 1-phosphate receptor 2 (S1pr2) agonist in pancreatic adenocarcinoma cell line (CFPAC-1).

Biochem/physiol Actions

CYM-5520 is a specific, noncompetitive allosteric agonist of sphingosine 1-phosphate receptor 2 (S1PR2; EC₅₀ = 1.0 μM). The compound CYM-5520 does not show any agonsit activity towards S1PR1, S1PR3, S1PR4 or S1PR5.

CYM-5520 mediates phosphorylation of transcription factor p65. It upregulates trabecular number, thickness as well as tibial bone volume density in osteoblasts.

UPC:: 41115852
Condition:: New
HazmatClass:: No
MPN:: SML1014-25MG
CAS:: 1449747-00-5

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