CX546 (C005B-025396)

General description

A positive allosteric modulator selective for the AMPA receptors. Used in studies related to Schizophrenia, neuroplasticity, Autism and neuronal differentiation.

Biochem/physiol Actions

Primary Target
AMPA

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Silverman, L., et al. 2013. Neuropharmacol.64, 268.
Peleg-Raibstein, D., et al. 2012. Curr. Antipsych.2012, 361.

Schitine, C., et al. 2012. Eur. J. Neurosci.35, 1672.
Lipina, T., et al. 2006. Neuropsychopharmacology.32, 745.
Arai, C., et al. 2004. Neurosci.123, 1011.
Nagarajan, N., et al. 2001. Neuropharmacol.41, 650.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Molecular Weight: 247.29. Empirical Formula: C₁₄H₁₇NO₃. Assay: ≥. 98% (TLC). Quality Level: 100. form: solid. manufacturer/tradename: Calbiochem^®. . storage condition: OK to freeze, protect from light. color: off-white. solubility: DMSO: soluble. storage temp.: 2-8°C. InChI: 1S/C14H17NO3/c16-14(15-6-2-1-3-7-15)11-4-5-12-13(10-11)18-9-8-17-12/h4-5,10H,1-3,6-9H2. InChI key: LJUNPHMOGNFFOS-UHFFFAOYSA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.