CVN636 is a potent, orally active and selective mGluR7 allosteric agonist with an EC 50 value of 7 nM for hu mGluR7 . CVN636 has central nervous system (CNS) permeabilityIn VivoCVN636 (0.3-3 mg/kg; p.o.) reduces ethanol self-administration in msP rats . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: msP rat Dosage: 0.3, 1, and 3 mg/kg Administration: oral administration Result: Reduced alcohol self-administration in a dose-dependent.IC50& Target:hu mGluR7 7 nM (EC 50 ).
Molecular Formula: C19H20FNO4S
Molecular Weight: 377.43
PubChem CID: 134521670
Isomeric SMILES: C[C@@H](C1=CC=C(C=C1)F)C(=O)N[C@H]2COC3=CC=CC=C3[C@@H]2S(=O)(=O)C
- UPC:
- 42181611
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- C651356-1mg
- CAS:
- 2226732-62-1
- Product Size:
- 1mg
akash.verma@cenmed.com
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