CVN424 is an orally active and selective GPR6 inverse agonist with a K i of 9.4 nM and an EC 50 of 38 nM. CVN424 is brain-penetrant and has the potential for Parkinson disease researchIn VitroCVN424 (Compound 6i) has 265 fold and 68 fold selectivities over GPR3 and GPR12. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:Ki: 9.4 nM (GPR6), EC50: 38 nM (GPR6).
Specifications and Purity: ≥99%
Molecular Formula: C24H29F2N5O3
Molecular Weight: 473.52
PubChem CID: 137359492
Isomeric SMILES: CC(=O)N1CCC2=C(C1)N=C(C(=N2)N3CCC(CC3)OC4=C(C=C(C=C4)F)F)N[C@@H]5CCOC5
- UPC:
- 41106620
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- C649899-10mg
- CAS:
- 2254706-21-1
- Product Size:
- 10mg
akash.verma@cenmed.com
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