CRISABOROLE (C005B-432804)

Catalog No.: C005B-432804
Manufacturer No.: PZ0037-5MG
Manufacturer Name: Sigma-Aldrich
Quantity: 5
Unit of Measure: MG

Biochem/physiol Actions Crisaborole is a non-steroidal anti-inflammatory phosphodiesterase 4 (PDE4) inhibitor. Crisaborole has an IC 50 value of 490 nM for PDE4 with similar IC 50 values for release of cytokines TNF-α:, IL-2, and

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Description
Specifications

Biochem/physiol Actions

Crisaborole is a non-steroidal anti-inflammatory phosphodiesterase 4 (PDE4) inhibitor. Crisaborole has an IC₅₀ value of 490 nM for PDE4 with similar IC₅₀ values for release of cytokines TNF-α, IL-2, and IFN-γ, and shows little inhibition against other PDE isozymes. Crisaborole has been approved as a topical treatment for atopic dermatitis.

Legal Information

Sold for research purposes under agreement from Pfizer Inc.

Pfizer is a registered trademark of Pfizer, Inc.

UPC:: 10161622
Condition:: New
HazmatClass:: No
MPN:: PZ0037-5MG
CAS:: 906673-24-3

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