CP-96345 (C005B-015119)

Biochem/physiol Actions

CP-96345 is a selective NK1 antagonist. CP96345 inhibits substance P-induced salivation in the rat by classical in vivo bioassay, but did not inhibit NK2, NK3, or numerous other receptors.

Features and Benefits

This compound was developed by Pfizer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Molecular Weight: 412.57. Empirical Formula: C₂₈H₃₂N₂O. Quality Level: 100. Assay: ≥. 98% (HPLC). form: powder. color: white. solubility: DMSO: 24 . mg/mL. originator: Pfizer. storage temp.: room temp. SMILES string: COC1: CC: CC: C1CN[C@@H]2[C@H](C(C3: CC: CC: C3)C4: CC: CC: C4)N5CCC2CC5. InChI: 1S/C28H32N2O/c1-31-25-15-9-8-14-24(25)20-29-27-23-16-18-30(19-17-23)28(27)26(21-10-4-2-5-11-21)22-12-6-3-7-13-22/h2-15,23,26-29H,16-20H2,1H3/t27-,28-/m0/s1. InChI key: FLNYLINBEZROPL-NSOVKSMOSA-N. Pictograms: GHS07,GHS09. Signal Word: Warning. Hazard Statements: H302 - H315 - H319 - H335 - H400. Precautionary Statements: P273 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338. Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3. Target Organs: Respiratory system. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.